{"id":9597,"date":"2026-11-03T00:27:23","date_gmt":"2026-11-02T23:27:23","guid":{"rendered":"https:\/\/www.s-vt.net\/?page_id=9597"},"modified":"2026-11-03T00:27:23","modified_gmt":"2026-11-02T23:27:23","slug":"eye-drops","status":"publish","type":"page","link":"https:\/\/www.s-vt.net\/ar\/eye-drops\/","title":{"rendered":"Eye Drops"},"content":{"rendered":"<div style='' class=''><section class='page-content' style=''  ><section class='container'><div style='' class=''><div class='row' style=''><div style='' class=''><div class='col-md-12 ' style=''><div style='' class=''><div class='cma-wysiwyg-editor'><p class=\"svt-lead2\">Eye drops are a dosage form of medicinal products for application to the eye. As oil-based or aqueous preparations, they enable the local action of the drugs they contain.<\/p><div class=\"svt-ptiles\"><div class=\"svt-ptile\"><i class=\"fa fa-shield\" aria-hidden=\"true\"><\/i><strong>Sterile manufacturing<\/strong><span>Pressure- and vacuum-resistant plants for GMP-compliant sterile production.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-tint\" aria-hidden=\"true\"><\/i><strong>pH value close to 7.4<\/strong><span>Well tolerated by the eye with optimum stability of the active ingredients.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-tachometer\" aria-hidden=\"true\"><\/i><strong>Process monitoring<\/strong><span>Measuring points for pH value, pressure, temperature and flow rate.<\/span><\/div><\/div><h2>Sterile manufacturing as a basic prerequisite<\/h2><p>Numerous regulations must be observed in the production of eye drops, and sterile manufacturing is a basic prerequisite. The mixing plants must therefore be designed for pressure- and vacuum-resistant sterile production. This is the only way to achieve the industrial manufacture of eye drops and other <a href=\"\/en\/pharmaceuticals\/\">pharmaceuticals<\/a> in line with GMP.<\/p><h2>pH value and stability of the active ingredients<\/h2><p>To prevent irritation of the eye, eye drops should have a pH value as close as possible to the physiological value of 7.4. At this pH value, however, most <a href=\"\/en\/active-ingredients\/\">active ingredients<\/a> are chemically unstable.<\/p><p>Manufacturing must therefore achieve optimum stability of the active ingredients without affecting the pH value or the osmotic pressure of the medicinal product. For this, the process plant should offer the following equipment:<\/p><ul class=\"svt-checks\"><li>Installation options in the homogeniser chamber for monitoring pH value, pressure, temperature and flow rate<\/li><li>Additional measuring points, e.g. for the pH value in the circulation line<\/li><\/ul><h2>Cleaning and sterilisation<\/h2><p>The <a href=\"\/cip-sip-systeme\/\">cleaning system (CIP)<\/a> is usually mounted on the lid and\/or the agitator. It must allow dead-space-free, straightforward and time-saving cleaning. Likewise, sterilisation of the plant (SIP) is a basic prerequisite for absolute sterility in vessels, pipework and valves.<\/p><h2>Frequently asked questions about manufacturing eye drops<\/h2><h3>What is a basic prerequisite for manufacturing eye drops?<\/h3><p>Sterile manufacturing. The mixing plants must therefore be pressure- and vacuum-resistant and designed for GMP-compliant sterile production, including CIP cleaning and SIP sterilisation.<\/p><h3>What pH value should eye drops have?<\/h3><p>As close as possible to the physiological pH value of 7.4 to avoid irritation. Since many active ingredients are unstable at this value, manufacturing must achieve stability without affecting the pH value and osmotic pressure.<\/p><h3>What measuring equipment does the plant need?<\/h3><p>Installation options for monitoring pH value, pressure, temperature and flow rate, e.g. in the homogeniser chamber or in the circulation line.<\/p><h3>How are the plants cleaned?<\/h3><p>Via a CIP system on the lid and\/or agitator that cleans without dead spaces and saves process time, plus SIP sterilisation for absolute sterility of vessels, pipework and valves.<\/p><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Service\",\"name\":\"Prozesstechnik f\u00fcr die Herstellung von Augentropfen\",\"description\":\"Beratung zu sterilen, druck- und vakuumfesten Prozessanlagen f\u00fcr Augentropfen mit pH-\u00dcberwachung, CIP und SIP nach GMP.\",\"url\":\"https:\/\/www.s-vt.net\/en\/eye-drops\/\",\"provider\":{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.s-vt.net\/#seefried\",\"name\":\"SEEFRIED Verfahrenstechnik GmbH\",\"url\":\"https:\/\/www.s-vt.net\/\",\"telephone\":\"+49 4203 789492\"},\"areaServed\":\"Worldwide\"},{\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What is a basic prerequisite for manufacturing eye drops?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Sterile manufacturing. The mixing plants must therefore be pressure- and vacuum-resistant and designed for GMP-compliant sterile production, including CIP cleaning and SIP sterilisation.\"}},{\"@type\":\"Question\",\"name\":\"What pH value should eye drops have?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"As close as possible to the physiological pH value of 7.4 to avoid irritation. Since many active ingredients are unstable at this value, manufacturing must achieve stability without affecting the pH value and osmotic pressure.\"}},{\"@type\":\"Question\",\"name\":\"What measuring equipment does the plant need?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Installation options for monitoring pH value, pressure, temperature and flow rate, e.g. in the homogeniser chamber or in the circulation line.\"}},{\"@type\":\"Question\",\"name\":\"How are the plants cleaned?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Via a CIP system on the lid and\/or agitator that cleans without dead spaces and saves process time, plus SIP sterilisation for absolute sterility of vessels, pipework and valves.\"}}]}]}<\/script><\/div><\/div><\/div><\/div><\/div><\/div><\/section><\/section><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","footnotes":""},"class_list":["post-9597","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sterile Eye Drop Manufacturing: Process Plants | SEEFRIED<\/title>\n<meta name=\"description\" content=\"Sterile manufacture of eye drops: pressure- and vacuum-resistant plants, pH monitoring, CIP cleaning and SIP sterilisation in line with GMP.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.s-vt.net\/ar\/eye-drops\/\" \/>\n<meta property=\"og:locale\" content=\"ar_AR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sterile Eye Drop Manufacturing: Process Plants | SEEFRIED\" \/>\n<meta property=\"og:description\" content=\"Sterile manufacture of eye drops: pressure- and vacuum-resistant plants, pH monitoring, CIP cleaning and SIP sterilisation in line with GMP.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.s-vt.net\/ar\/eye-drops\/\" \/>\n<meta property=\"og:site_name\" content=\"SEEFRIED Verfahrenstechnik GmbH\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.s-vt.net\\\/ar\\\/eye-drops\\\/\",\"url\":\"https:\\\/\\\/www.s-vt.net\\\/ar\\\/eye-drops\\\/\",\"name\":\"Sterile Eye Drop Manufacturing: Process Plants | SEEFRIED\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.s-vt.net\\\/#website\"},\"datePublished\":\"2026-11-02T23:27:23+00:00\",\"description\":\"Sterile manufacture of eye drops: pressure- and vacuum-resistant plants, pH monitoring, CIP cleaning and SIP sterilisation in line with GMP.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.s-vt.net\\\/ar\\\/eye-drops\\\/#breadcrumb\"},\"inLanguage\":\"ar\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.s-vt.net\\\/ar\\\/eye-drops\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.s-vt.net\\\/ar\\\/eye-drops\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/www.s-vt.net\\\/ar\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Eye Drops\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.s-vt.net\\\/#website\",\"url\":\"https:\\\/\\\/www.s-vt.net\\\/\",\"name\":\"SEEFRIED Verfahrenstechnik GmbH\",\"description\":\"\u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u062e\u0644\u0637 \u0648\u0647\u0646\u062f\u0633\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0639\u0644\u0649 \u0623\u064a\u062f\u064a \u062e\u0628\u0631\u0627\u0621\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.s-vt.net\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ar\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sterile Eye Drop Manufacturing: Process Plants | SEEFRIED","description":"Sterile manufacture of eye drops: pressure- and vacuum-resistant plants, pH monitoring, CIP cleaning and SIP sterilisation in line with GMP.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.s-vt.net\/ar\/eye-drops\/","og_locale":"ar_AR","og_type":"article","og_title":"Sterile Eye Drop Manufacturing: Process Plants | SEEFRIED","og_description":"Sterile manufacture of eye drops: pressure- and vacuum-resistant plants, pH monitoring, CIP cleaning and SIP sterilisation in line with GMP.","og_url":"https:\/\/www.s-vt.net\/ar\/eye-drops\/","og_site_name":"SEEFRIED Verfahrenstechnik GmbH","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.s-vt.net\/ar\/eye-drops\/","url":"https:\/\/www.s-vt.net\/ar\/eye-drops\/","name":"Sterile Eye Drop Manufacturing: Process Plants | SEEFRIED","isPartOf":{"@id":"https:\/\/www.s-vt.net\/#website"},"datePublished":"2026-11-02T23:27:23+00:00","description":"Sterile manufacture of eye drops: pressure- and vacuum-resistant plants, pH monitoring, CIP cleaning and SIP sterilisation in line with GMP.","breadcrumb":{"@id":"https:\/\/www.s-vt.net\/ar\/eye-drops\/#breadcrumb"},"inLanguage":"ar","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.s-vt.net\/ar\/eye-drops\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.s-vt.net\/ar\/eye-drops\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/www.s-vt.net\/ar\/"},{"@type":"ListItem","position":2,"name":"Eye Drops"}]},{"@type":"WebSite","@id":"https:\/\/www.s-vt.net\/#website","url":"https:\/\/www.s-vt.net\/","name":"SEEFRIED Verfahrenstechnik GmbH","description":"\u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u062e\u0644\u0637 \u0648\u0647\u0646\u062f\u0633\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0639\u0644\u0649 \u0623\u064a\u062f\u064a \u062e\u0628\u0631\u0627\u0621","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.s-vt.net\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ar"}]}},"_links":{"self":[{"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/pages\/9597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/comments?post=9597"}],"version-history":[{"count":1,"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/pages\/9597\/revisions"}],"predecessor-version":[{"id":9598,"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/pages\/9597\/revisions\/9598"}],"wp:attachment":[{"href":"https:\/\/www.s-vt.net\/ar\/wp-json\/wp\/v2\/media?parent=9597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}