{"id":9603,"date":"2026-11-03T00:28:05","date_gmt":"2026-11-02T23:28:05","guid":{"rendered":"https:\/\/www.s-vt.net\/?page_id=9603"},"modified":"2026-11-03T00:28:05","modified_gmt":"2026-11-02T23:28:05","slug":"vaccines","status":"publish","type":"page","link":"https:\/\/www.s-vt.net\/ar\/vaccines\/","title":{"rendered":"Vaccines"},"content":{"rendered":"<div style='' class=''><section class='page-content' style=''  ><section class='container'><div style='' class=''><div class='row' style=''><div style='' class=''><div class='col-md-12 ' style=''><div style='' class=''><div class='cma-wysiwyg-editor'><p class=\"svt-lead2\">The manufacture of vaccines requires the highest precision. Vaccines differ from other <a href=\"\/en\/pharmaceuticals\/\">pharmaceutical products<\/a> in that they can contain biological substances and, in certain cases, even live pathogens.<\/p><div class=\"svt-ptiles\"><div class=\"svt-ptile\"><i class=\"fa fa-expand\" aria-hidden=\"true\"><\/i><strong>Precise scale-up<\/strong><span>Identical design from laboratory to production plant.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-shield\" aria-hidden=\"true\"><\/i><strong>Aseptic &amp; GMP<\/strong><span>Aseptic valves and fittings, CIP and SIP for the highest hygiene.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-database\" aria-hidden=\"true\"><\/i><strong>Complete documentation<\/strong><span>Recipe control with continuous recording of all processes.<\/span><\/div><\/div><h2>Special requirements for production<\/h2><p>Vaccines require significantly longer production cycles. In addition, extremely strict safety and quality criteria apply, and quality controls take up a large part of the total production time. The specific nature of the components makes production even more difficult.<\/p><h2>Requirements for the process plant<\/h2><p>The machines used must therefore meet all production-relevant aspects. The following are particularly important:<\/p><ul class=\"svt-checks\"><li>Precise scale-up from laboratory scale to production plant through identical design and performance rating of the <a href=\"\/en\/agitation\/\">agitating<\/a> and <a href=\"\/en\/homogenisation\/\">homogenising machines<\/a><\/li><li>Consistently high product quality in every plant size<\/li><li>Aseptic valves and fittings and GMP-compliant plant design<\/li><li>Integrated <a href=\"\/cip-sip-systeme\/\">cleaning systems (CIP)<\/a> for dead-space-free cleaning<\/li><li>Germ-free sterilisation of the plant (SIP)<\/li><\/ul><h2>Control and documentation<\/h2><p>Also of great importance is the precise documentation of all production steps by means of <a href=\"\/software-schnittstellenbeschreibungen\/\">powerful software<\/a>. Modern process plants offer suitable solutions for this \u2013 from a small recipe control with a separate recorder to large-scale visualisation on a touch panel.<\/p><p>Large solutions include an integrated recipe sequence for production and cleaning steps and continuous documentation in the background. In addition, the plant can be operated from a central <a href=\"\/steuerungen\/\">control system<\/a> station.<\/p><h2>FAQ: Plants for vaccine manufacturing<\/h2><h3>What is particularly important in vaccine manufacturing?<\/h3><p>Vaccines contain biological substances, in some cases live or inactivated pathogens. Sterility, aseptic processing, gentle process control, complete documentation and extensive quality controls are crucial.<\/p><h3>What role do agitating and homogenising machines play?<\/h3><p>They are used, for example, in formulation, mixing with adjuvants and emulsifying. Gentle energy input, aseptic valves and fittings, GMP design as well as CIP and SIP are important.<\/p><h3>How is scale-up from the laboratory to production achieved?<\/h3><p>Through laboratory, pilot and production machines with identical design and the same performance rating. This allows process parameters to be transferred directly.<\/p><h3>Why is process documentation so important?<\/h3><p>For batch release, all production and cleaning steps must be traceable. Modern control systems with recipe management and audit trail record all data automatically.<\/p><h3>Does SEEFRIED support projects in vaccine production?<\/h3><p>Yes, with process plant planning, qualification (DQ\/IQ\/OQ\/PQ) and suitable agitating and homogenising plants.<\/p><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Service\",\"name\":\"Prozessanlagen f\u00fcr die Impfstoffherstellung\",\"description\":\"Planung, Qualifizierung und Lieferung GMP-gerechter, aseptischer R\u00fchr- und Homogenisieranlagen f\u00fcr Impfstoffe.\",\"url\":\"https:\/\/www.s-vt.net\/en\/vaccines\/\",\"provider\":{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.s-vt.net\/#seefried\",\"name\":\"SEEFRIED Verfahrenstechnik GmbH\",\"url\":\"https:\/\/www.s-vt.net\/\",\"telephone\":\"+49 4203 789492\"},\"areaServed\":\"Worldwide\"},{\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What is particularly important in vaccine manufacturing?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Vaccines contain biological substances, in some cases live or inactivated pathogens. 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Modern control systems with recipe management and audit trail record all data automatically.\"}},{\"@type\":\"Question\",\"name\":\"Does SEEFRIED support projects in vaccine production?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, with process plant planning, qualification (DQ\/IQ\/OQ\/PQ) and suitable agitating and homogenising plants.\"}}]}]}<\/script><\/div><\/div><\/div><\/div><\/div><\/div><\/section><\/section><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","footnotes":""},"class_list":["post-9603","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Vaccine Manufacturing: GMP Process Plants | SEEFRIED<\/title>\n<meta name=\"description\" content=\"Plants for vaccine production: aseptic design, CIP\/SIP, scale-up, complete documentation. 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