{"id":3992,"date":"2016-05-03T10:09:02","date_gmt":"2016-05-03T08:09:02","guid":{"rendered":"http:\/\/mirror.s-vt.net\/wirkstoffe\/"},"modified":"2026-10-26T15:14:28","modified_gmt":"2026-10-26T14:14:28","slug":"active-substances","status":"publish","type":"page","link":"https:\/\/www.s-vt.net\/en\/active-substances\/","title":{"rendered":"Active Substances"},"content":{"rendered":"

The production of active substances involves processes that must be carried out precisely, quickly, efficiently and gently. A conventional agitator alone cannot handle this task.<\/p>

<\/i>Rotor\/stator system<\/strong>Reduce solids and increase the powder surface area.<\/span><\/div>
<\/i>Variable process parameters<\/strong>Variable speed for agitator and homogeniser.<\/span><\/div>
<\/i>Expandable<\/strong>Plants that grow with new requirements.<\/span><\/div><\/div>

High-performance agitation and homogenising systems<\/h2>

Process plants with integrated, powerful agitation and homogenising systems are therefore used. Their rotor\/stator system ensures optimal size reduction of the solids and at the same time increases the surface area of the powder in the liquid. This produces agglomerate-free solutions within a few minutes.<\/p>

Breaking up the agglomerates<\/a> makes the entire particle surface accessible to the liquid. As a result, active substances dissolve faster and more evenly, suspensions<\/a> become more homogeneous and dosing accuracy increases.<\/p>

For poorly soluble active substances, a finer particle size can improve the dissolution rate and thus bioavailability. True micronisation down to a few micrometres, however, usually requires jet mills, bead mills or high-pressure homogenisers. The rotor\/stator homogeniser mainly handles deagglomeration, wetting and dispersion.<\/p>

Requirements for the plant<\/h2>