{"id":3998,"date":"2016-05-03T10:03:14","date_gmt":"2016-05-03T08:03:14","guid":{"rendered":"http:\/\/mirror.s-vt.net\/pasten\/"},"modified":"2026-10-26T15:12:57","modified_gmt":"2026-10-26T14:12:57","slug":"pastes","status":"publish","type":"page","link":"https:\/\/www.s-vt.net\/en\/pastes\/","title":{"rendered":"Pastes"},"content":{"rendered":"<section class='page-content' style=''  ><section class='container'><div class='row' style=''><div class='col-md-12 ' style=''><div class='cma-wysiwyg-editor'><p class=\"svt-lead2\">In the production of pharmaceutical pastes, base substances and <a href=\"\/active-substances\/?lang=en\">active ingredients<\/a> are combined into a stable, durable and effective finished preparation. These pastes are intended for external use.<\/p><div class=\"svt-ptiles\"><div class=\"svt-ptile\"><i class=\"fa fa-pie-chart\" aria-hidden=\"true\"><\/i><strong>25 to 50 % solids<\/strong><span>Disperse or dissolve powders into a fine distribution.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-tint\" aria-hidden=\"true\"><\/i><strong>Highly viscous<\/strong><span>Safe handling of substances with different viscosities.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-refresh\" aria-hidden=\"true\"><\/i><strong>In the vessel or in recirculation<\/strong><span>Homogenising with variable speed.<\/span><\/div><\/div><h2>Effect and composition<\/h2><p>Many pharmaceutical pastes dry out wounds and have a secretion-binding and antiseptic effect. For this purpose, active ingredients and other components with different consistencies are combined.<\/p><p>At the start, the components are often in powder form. During production, they must be <a href=\"\/dispersion\/?lang=en\">dispersed<\/a> or dissolved so that a finely distributed dispersion is formed with the other ingredients. Depending on the product, the solids content is between 25 % and 50 %.<\/p><h2>Requirements for the production plant<\/h2><p>In addition to hygienic production, handling substances with different viscosities is crucial. Modern plants can be used flexibly and efficiently for this purpose:<\/p><ul class=\"svt-checks\"><li><a href=\"\/homogenisation\/?lang=en\">homogenisation<\/a> in the vessel or in the recirculation process<\/li><li>variable speed for efficient yet gentle processing<\/li><li>powder induction under vacuum for a high solids content<\/li><li>hygienic, GMP-compliant design with <a href=\"\/cip-sip-systems\/?lang=en\">CIP cleaning<\/a><\/li><\/ul><h2>FAQ: Producing pharmaceutical pastes<\/h2><h3>What distinguishes pastes from ointments?<\/h3><p>Pastes are semi-solid preparations with a high solids content (typically 25 to 50 %), e.g. zinc oxide. They adhere well, dry wounds and bind secretions.<\/p><h3>How are high powder loads incorporated?<\/h3><p>Powders are drawn in step by step under vacuum and dispersed with a rotor-stator homogeniser until a fine, agglomerate-free distribution is achieved.<\/p><h3>Which machine is suitable for pastes?<\/h3><p>Vacuum homogenising mixers with a powerful scraper agitator, homogeniser in the vessel or recirculation loop and variable speed for high-viscosity products.<\/p><h3>How is air entrapment avoided?<\/h3><p>By processing and deaerating under vacuum and using low speeds during powder induction.<\/p><h3>Does SEEFRIED supply plants for pastes?<\/h3><p>Yes, SEEFRIED Verfahrenstechnik plans plants for semi-solid dosage forms and offers inspected used vacuum homogenising mixers.<\/p><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Service\",\"name\":\"Process plants for pharmaceutical pastes\",\"description\":\"Planning and supply of vacuum homogenising mixers for pastes with high solids content.\",\"url\":\"https:\/\/www.s-vt.net\/pastes\/?lang=en\",\"provider\":{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.s-vt.net\/#seefried\",\"name\":\"SEEFRIED Verfahrenstechnik GmbH\",\"url\":\"https:\/\/www.s-vt.net\/\",\"telephone\":\"+49 4203 789492\"},\"areaServed\":\"Worldwide\"},{\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What distinguishes pastes from ointments?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Pastes are semi-solid preparations with a high solids content (typically 25 to 50 %), e.g. zinc oxide. 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Plants and consulting from SEEFRIED.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.s-vt.net\/pastes\/?lang=en\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pharmaceutical Paste Production: Mixers | SEEFRIED\" \/>\n<meta property=\"og:description\" content=\"Producing pastes with 25 to 50 % solids: vacuum powder induction, homogenising, high-viscosity processing. 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