{"id":10016,"date":"2026-11-03T01:25:21","date_gmt":"2026-11-03T00:25:21","guid":{"rendered":"https:\/\/www.s-vt.net\/?page_id=10016"},"modified":"2026-11-03T01:25:21","modified_gmt":"2026-11-03T00:25:21","slug":"supozituvarlar","status":"publish","type":"page","link":"https:\/\/www.s-vt.net\/tr\/supozituvarlar\/","title":{"rendered":"S\u00fcpozituvarlar"},"content":{"rendered":"<div style='' class=''><section class='page-content' style=''  ><section class='container'><div style='' class=''><div class='row' style=''><div style='' class=''><div class='col-md-12 ' style=''><div style='' class=''><div class='cma-wysiwyg-editor'><p class=\"svt-lead2\">S\u00fcpozituvarlar, ya\u011f i\u00e7eren ve suda \u00e7\u00f6z\u00fcnen preparatlar olarak ikiye ayr\u0131l\u0131r. Ya\u011f i\u00e7eren fitiller daha yayg\u0131n bilinen formdur.<\/p><div class=\"svt-ptiles\"><div class=\"svt-ptile\"><i class=\"fa fa-fire\" aria-hidden=\"true\"><\/i><strong>Hassas s\u0131cakl\u0131k kontrol\u00fc<\/strong><span>\u00dcr\u00fcnle temas eden t\u00fcm par\u00e7alar\u0131n kademesiz ayarlanabilir \u0131s\u0131t\u0131lmas\u0131 ve so\u011futulmas\u0131.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-refresh\" aria-hidden=\"true\"><\/i><strong>Sirk\u00fclasyon kar\u0131\u015ft\u0131r\u0131c\u0131s\u0131<\/strong><span>Gerekti\u011finde minimum kesmeyle y\u00fcksek kar\u0131\u015f\u0131m.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-database\" aria-hidden=\"true\"><\/i><strong>Eksiksiz dok\u00fcmantasyon<\/strong><span>T\u00fcm \u00fcretim ad\u0131mlar\u0131 kaydedilir ve saklan\u0131r.<\/span><\/div><\/div><h2>Ya\u011f i\u00e7eren ve suda \u00e7\u00f6z\u00fcnen s\u00fcpozituvarlar<\/h2><div class=\"svt-kgrid svt-kgrid-2\"><div class=\"svt-kcard\"><i class=\"fa fa-tint\" aria-hidden=\"true\"><\/i><h3>Ya\u011f i\u00e7eren<\/h3><p>Baz olarak \u00e7o\u011funlukla erime aral\u0131\u011f\u0131 v\u00fccut s\u0131cakl\u0131\u011f\u0131na yak\u0131n olan sert ya\u011f kullan\u0131l\u0131r. B\u00f6ylece fitil uygulama yerinde \u00e7\u00f6z\u00fcn\u00fcr. Bunun i\u00e7in sert ya\u011f\u0131n tan\u0131ml\u0131 em\u00fclsiyon ve erime \u00f6zelliklerine sahip olmas\u0131 gerekir.<\/p><\/div><div class=\"svt-kcard\"><i class=\"fa fa-flask\" aria-hidden=\"true\"><\/i><h3>Suda \u00e7\u00f6z\u00fcnen<\/h3><p>Bu fitiller erimez; mevcut suyun i\u00e7inde \u00e7\u00f6z\u00fcn\u00fcr ve ard\u0131ndan etken maddeyi serbest b\u0131rak\u0131r. Farkl\u0131 polietilen glikollerin (makrogol) kar\u0131\u015f\u0131mlar\u0131 ile jelatin ve gliserol kullan\u0131l\u0131r.<\/p><\/div><\/div><p class=\"svt-knote\">Suda \u00e7\u00f6z\u00fcnen s\u00fcpozituvarlarda bir zorluk, fitilin \u00e7\u00f6z\u00fcnmesi gereken uygulama yerindeki (\u00f6rn. rektumdaki) s\u0131v\u0131 miktar\u0131n\u0131n az olmas\u0131d\u0131r.<\/p><p>S\u00fcpozituvarlar \u015funlardan olu\u015fur: <a href=\"\/tr\/emulsiyon\/\">em\u00fclsiyonlar<\/a>, <a href=\"\/tr\/suspansiyon\/\">s\u00fcspansiyonlar<\/a> veya farkl\u0131 <a href=\"\/tr\/etken-maddeler\/\">etken maddelerin<\/a> ve sert ya\u011flar\u0131n \u00e7\u00f6zeltileri.<\/p><h2>Homojenizat\u00f6r miksere y\u00f6nelik gereksinimler<\/h2><p>Hijyenik \u00fcretimin yan\u0131 s\u0131ra \u00e7ok farkl\u0131 viskozitelerin i\u015flenmesi belirleyicidir. Modern homojenizat\u00f6r mikserler bunun i\u00e7in esnek ve verimli \u015fekilde kullan\u0131labilir:<\/p><ul class=\"svt-checks\"><li>verimli emme, harmanlama ve dozaj i\u00e7in homojenizat\u00f6r haznesinde, sirk\u00fclasyon hatt\u0131nda ve kapakta montaj ve donan\u0131m imk\u00e2nlar\u0131<\/li><li>tek bir homojenizasyon ad\u0131m\u0131nda steril i\u015fleme i\u00e7in bas\u0131nca ve vakuma dayan\u0131kl\u0131 s\u0131zd\u0131rmazl\u0131k elemanlar\u0131<\/li><li>y\u00fcksek viskoziteli k\u00fctlelerde bile verimli radyal ve dikey kar\u0131\u015f\u0131m<\/li><li>rahat emme ve <a href=\"\/tr\/kati-sivi-karistirma\/\">tozlar\u0131n dispersiyonu<\/a> ya da mum peletlerinin kar\u0131\u015f\u0131ma kat\u0131lmas\u0131<\/li><li>standart olarak aseptik armat\u00fcrler<\/li><\/ul><h2>\u00c7apa tipi kar\u0131\u015ft\u0131r\u0131c\u0131 yerine sirk\u00fclasyon kar\u0131\u015ft\u0131r\u0131c\u0131s\u0131<\/h2><p>Bir\u00e7ok s\u00fcpozituvar k\u00fctlesi, s\u0131y\u0131r\u0131c\u0131l\u0131 \u00e7apa tipi kar\u0131\u015ft\u0131r\u0131c\u0131 olmadan da \u00fcretilebilir. Bunun yerine sirk\u00fclasyon kar\u0131\u015ft\u0131r\u0131c\u0131lar\u0131 veya benzeri kar\u0131\u015ft\u0131r\u0131c\u0131lar kullan\u0131l\u0131r.<\/p><p>Sirk\u00fclasyon kar\u0131\u015ft\u0131r\u0131c\u0131s\u0131yla ya\u011f fazlar\u0131 eritilebilir ve mumlar kar\u0131\u015f\u0131ma kat\u0131labilir. Ayn\u0131 zamanda \u00fcr\u00fcn s\u00fcrekli hareket halinde kal\u0131r \u2013 istenirse y\u00fcksek kar\u0131\u015f\u0131mda minimum kesmeyle.<\/p><h2>S\u0131cakl\u0131k kontrol\u00fc ve dok\u00fcmantasyon<\/h2><p>Hassas, kademesiz ayarlanabilir bir s\u0131cakl\u0131k kontrol\u00fc, tam olarak uyumlu \u0131s\u0131tma ve so\u011futma fazlar\u0131 sa\u011flar. Bunun i\u00e7in \u00fcr\u00fcnle temas eden t\u00fcm tesis par\u00e7alar\u0131n\u0131n temperlenebilir olmas\u0131 gerekir. Ayr\u0131ca t\u00fcm \u00fcretim ad\u0131mlar\u0131 kaydedilir, saklan\u0131r ve her an eri\u015filebilir durumdad\u0131r.<\/p><h2>SSS: S\u00fcpozituvar \u00fcretimi<\/h2><h3>S\u00fcpozituvarlar nelerden olu\u015fur?<\/h3><p>\u00c7o\u011funlukla erime aral\u0131\u011f\u0131 v\u00fccut s\u0131cakl\u0131\u011f\u0131na yak\u0131n sert ya\u011fdan, alternatif olarak makrogoller (polietilen glikoller) veya gliserol-jelatin gibi suda \u00e7\u00f6z\u00fcnen bazlardan. Etken maddeler \u00e7\u00f6z\u00fcl\u00fcr, em\u00fclsifiye edilir veya s\u00fcspanse edilir.<\/p><h3>S\u00fcpozituvar k\u00fctlesi nas\u0131l \u00fcretilir?<\/h3><p>Sert ya\u011f eritilir, etken maddeler kat\u0131l\u0131r ve homojen \u015fekilde dispers edilir. K\u00fctle, kat\u0131lar\u0131n \u00e7\u00f6kmemesi i\u00e7in temperlenmi\u015f halde hareket ettirilir ve ard\u0131ndan kal\u0131plara d\u00f6k\u00fcl\u00fcr.<\/p><h3>Hangi kar\u0131\u015ft\u0131r\u0131c\u0131 uygundur?<\/h3><p>\u00c7o\u011funlukla d\u00fc\u015f\u00fck kesmeyle y\u00fcksek kar\u0131\u015f\u0131m sa\u011flayan bir sirk\u00fclasyon kar\u0131\u015ft\u0131r\u0131c\u0131s\u0131. S\u0131y\u0131r\u0131c\u0131l\u0131 \u00e7apa tipi kar\u0131\u015ft\u0131r\u0131c\u0131 bir\u00e7ok k\u00fctle i\u00e7in gerekli de\u011fildir.<\/p><h3>S\u0131cakl\u0131k kontrol\u00fc neden bu kadar \u00f6nemlidir?<\/h3><p>Viskozite, \u00e7\u00f6kme davran\u0131\u015f\u0131 ve d\u00f6k\u00fclebilirli\u011fin sabit kalmas\u0131 i\u00e7in k\u00fctle erime noktas\u0131n\u0131n hemen \u00fczerinde tutulmal\u0131d\u0131r. \u00dcr\u00fcnle temas eden t\u00fcm par\u00e7alar temperlenebilir olmal\u0131d\u0131r.<\/p><h3>SEEFRIED s\u00fcpozituvar k\u00fctleleri i\u00e7in tesis sunuyor mu?<\/h3><p>Evet; s\u00fcpozituvarlar ve ov\u00fcller i\u00e7in tesisler planl\u0131yor ve uygun kar\u0131\u015ft\u0131r\u0131c\u0131l\u0131 homojenizat\u00f6r mikserler tedarik ediyoruz.<\/p><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Service\",\"name\":\"S\u00fcpozituvar \u00fcretimi i\u00e7in proses tesisleri\",\"description\":\"S\u00fcpozituvar ve ov\u00fcl k\u00fctleleri i\u00e7in s\u0131cakl\u0131k kontroll\u00fc kar\u0131\u015ft\u0131rma ve homojenizasyon tesislerinin planlanmas\u0131 ve teslimat\u0131.\",\"url\":\"https:\/\/www.s-vt.net\/tr\/supozituvarlar\/\",\"provider\":{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.s-vt.net\/#seefried\",\"name\":\"SEEFRIED Verfahrenstechnik GmbH\",\"url\":\"https:\/\/www.s-vt.net\/\",\"telephone\":\"+49 4203 789492\"},\"areaServed\":\"Worldwide\"},{\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"S\u00fcpozituvarlar nelerden olu\u015fur?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"\u00c7o\u011funlukla erime aral\u0131\u011f\u0131 v\u00fccut s\u0131cakl\u0131\u011f\u0131na yak\u0131n sert ya\u011fdan, alternatif olarak makrogoller (polietilen glikoller) veya gliserol-jelatin gibi suda \u00e7\u00f6z\u00fcnen bazlardan. 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