{"id":18988,"date":"2026-11-11T22:50:23","date_gmt":"2026-11-11T21:50:23","guid":{"rendered":"https:\/\/www.s-vt.net\/he-thong-cip-sip\/"},"modified":"2026-11-11T23:20:02","modified_gmt":"2026-11-11T22:20:02","slug":"cip-sip-systems","status":"publish","type":"page","link":"https:\/\/www.s-vt.net\/vi\/cip-sip-systems\/","title":{"rendered":"H\u1ec7 th\u1ed1ng CIP \u2013 SIP"},"content":{"rendered":"<div style='' class=''><section class='page-content' style=''  ><section class='container'><div style='' class=''><div class='row' style=''><div style='' class=''><div class='col-md-12 ' style=''><div style='' class=''><div class='cma-wysiwyg-editor'><p class=\"svt-lead2\">Quy tr\u00ecnh CIP (Cleaning in Place \u2013 v\u1ec7 sinh t\u1ea1i ch\u1ed7) bao g\u1ed3m c\u00e1c qu\u00e1 tr\u00ecnh c\u01a1 h\u1ecdc v\u00e0 h\u00f3a h\u1ecdc, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ch\u1ee7 y\u1ebfu trong ng\u00e0nh <a href=\"https:\/\/www.s-vt.net\/vi\/pharmaceuticals\/\">d\u01b0\u1ee3c ph\u1ea9m,<\/a> <a href=\"https:\/\/www.s-vt.net\/vi\/cosmetics\/\">m\u1ef9 ph\u1ea9m<\/a> v\u00e0 th\u1ef1c ph\u1ea9m. Theo \u0111\u00f3, b\u1ed3n ch\u1ee9a, \u0111\u01b0\u1eddng \u1ed1ng v\u00e0 van \u0111\u01b0\u1ee3c v\u1ec7 sinh gi\u1eefa c\u00e1c m\u1ebb s\u1ea3n xu\u1ea5t tr\u00ean m\u1ecdi b\u1ec1 m\u1eb7t ti\u1ebfp x\u00fac v\u1edbi s\u1ea3n ph\u1ea9m \u2013 m\u00e0 kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi tr\u01b0\u1edbc.<\/p><div class=\"svt-ptiles\"><div class=\"svt-ptile\"><i class=\"fa fa-refresh\" aria-hidden=\"true\"><\/i><strong>V\u1ec7 sinh kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi<\/strong><span>B\u1ed3n ch\u1ee9a, \u0111\u01b0\u1eddng \u1ed1ng v\u00e0 van \u0111\u01b0\u1ee3c v\u1ec7 sinh ngay \u1edf tr\u1ea1ng th\u00e1i l\u1eafp \u0111\u1eb7t.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-fire\" aria-hidden=\"true\"><\/i><strong>Ti\u1ec7t tr\u00f9ng b\u1eb1ng h\u01a1i s\u1ea1ch<\/strong><span>SIP ti\u1ec7t tr\u00f9ng m\u1ecdi b\u1ed9 ph\u1eadn ti\u1ebfp x\u00fac v\u1edbi s\u1ea3n ph\u1ea9m, th\u01b0\u1eddng \u1edf 121 \u00b0C.<\/span><\/div><div class=\"svt-ptile\"><i class=\"fa fa-check-square-o\" aria-hidden=\"true\"><\/i><strong>L\u1eb7p l\u1ea1i \u0111\u01b0\u1ee3c &amp; c\u00f3 h\u1ed3 s\u01a1<\/strong><span>Quy tr\u00ecnh ho\u00e0n to\u00e0n t\u1ef1 \u0111\u1ed9ng v\u1edbi h\u1ed3 s\u01a1 \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 qu\u00e1 tr\u00ecnh v\u1ec7 sinh.<\/span><\/div><\/div><p>Kinh nghi\u1ec7m th\u1ef1c t\u1ebf v\u00e0 th\u1eed nghi\u1ec7m cho th\u1ea5y: hi\u1ec7u qu\u1ea3 v\u1ec7 sinh c\u01a1 h\u1ecdc ph\u1ee5 thu\u1ed9c v\u00e0o v\u1eadn t\u1ed1c d\u00f2ng ch\u1ea3y v\u00e0 \u0111\u1ed9 r\u1ed1i c\u1ee7a ch\u1ea5t l\u1ecfng v\u1ec7 sinh. Ngo\u00e0i ra, nhi\u1ec7t \u0111\u1ed9 v\u00e0 n\u1ed3ng \u0111\u1ed9 dung d\u1ecbch v\u1ec7 sinh \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u1ed1c \u0111\u1ed9 v\u1ec7 sinh. V\u00ec v\u1eady, c\u00e1c y\u1ebfu t\u1ed1 n\u00e0y n\u00ean \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh ngay khi thi\u1ebft k\u1ebf h\u1ec7 th\u1ed1ng v\u1ec7 sinh.<\/p><h2>An to\u00e0n s\u1ea3n ph\u1ea9m, v\u1ec7 sinh v\u00e0 hi\u1ec7u qu\u1ea3<\/h2><p>Quy tr\u00ecnh CIP gi\u1eef vai tr\u00f2 trung t\u00e2m \u0111\u1ed1i v\u1edbi an to\u00e0n s\u1ea3n ph\u1ea9m v\u00e0 v\u1ec7 sinh. \u0110\u1ed3ng th\u1eddi, h\u1ec7 th\u1ed1ng c\u1ea7n v\u1eadn h\u00e0nh hi\u1ec7u qu\u1ea3 nh\u1ea5t c\u00f3 th\u1ec3 v\u00e0 ch\u1ec9 d\u1eebng trong th\u1eddi gian ng\u1eafn. \u0110\u1eb7c bi\u1ec7t quan tr\u1ecdng l\u00e0 chi ph\u00ed n\u01b0\u1edbc v\u00e0 n\u0103ng l\u01b0\u1ee3ng ng\u00e0y c\u00e0ng t\u0103ng c\u0169ng nh\u01b0 m\u1ee9c ti\u00eau th\u1ee5 h\u00f3a ch\u1ea5t ph\u00f9 h\u1ee3p v\u1edbi t\u1eebng s\u1ea3n ph\u1ea9m.<\/p><p>Do \u0111\u00f3, ng\u01b0\u1eddi ph\u00e1t tri\u1ec3n quy tr\u00ecnh v\u1ec7 sinh ph\u1ea3i hi\u1ec3u r\u00f5 \u0111\u1eb7c t\u00ednh c\u1ee7a t\u00e1 d\u01b0\u1ee3c v\u00e0 ho\u1ea1t ch\u1ea5t, \u0111\u1ed3ng th\u1eddi l\u1ef1a ch\u1ecdn ch\u1ea5t t\u1ea9y r\u1eeda ph\u00f9 h\u1ee3p. M\u1ed9t ch\u1ea5t t\u1ea9y r\u1eeda kh\u00f4ng ph\u00f9 h\u1ee3p c\u00f3 th\u1ec3 k\u00e9o d\u00e0i \u0111\u00e1ng k\u1ec3 th\u1eddi gian v\u1ec7 sinh, th\u1eadm ch\u00ed khi\u1ebfn kh\u00f4ng th\u1ec3 v\u1ec7 sinh ho\u00e0n to\u00e0n.<\/p><p>M\u1ee9c \u0111\u1ed9 tri\u1ec7t \u0111\u1ec3 c\u1ee7a vi\u1ec7c v\u1ec7 sinh ph\u1ee5 thu\u1ed9c v\u00e0o nhi\u1ec1u y\u1ebfu t\u1ed1. B\u00ean c\u1ea1nh lo\u1ea1i ch\u1ea5t b\u1ea9n, c\u00f2n c\u00f3 \u0111\u1eb7c t\u00ednh c\u1ee7a c\u00e1c b\u1ec1 m\u1eb7t ti\u1ebfp x\u00fac v\u1edbi m\u00f4i ch\u1ea5t v\u00e0 c\u00e1ch l\u1eafp \u0111\u1eb7t ch\u00fang. C\u00e1c g\u00f3c, c\u1ea1nh, c\u00e1ch b\u1ed1 tr\u00ed gio\u0103ng v\u00e0 v\u00f9ng d\u00f2ng ch\u1ea3y y\u1ebfu \u2013 ch\u1eb3ng h\u1ea1n trong c\u00e1c \u0111o\u1ea1n ch\u1eef T, ch\u1ed7 \u0111\u1ecdng n\u01b0\u1edbc ho\u1eb7c v\u00f2m \u2013 c\u0169ng nh\u01b0 \u0111i\u1ec1u ki\u1ec7n v\u1eadn h\u00e0nh c\u0169ng c\u00f3 \u00fd ngh\u0129a quy\u1ebft \u0111\u1ecbnh.<\/p><h2>Hi\u1ec7u qu\u1ea3 v\u1ec7 sinh ph\u1ee5 thu\u1ed9c v\u00e0o \u0111\u00e2u<\/h2><ul class=\"svt-checks\"><li>c\u00e1c bi\u1ec7n ph\u00e1p k\u1ebft c\u1ea5u t\u1ea1i nh\u1eefng khu v\u1ef1c c\u1ea7n v\u1ec7 sinh c\u1ee7a h\u1ec7 th\u1ed1ng (<a href=\"https:\/\/www.s-vt.net\/vi\/design-qualification\/\">GMP \u2013 Good Manufacturing Practice<\/a>)<\/li><li>l\u1ef1a ch\u1ecdn v\u1eadt li\u1ec7u v\u00e0 t\u00ecnh tr\u1ea1ng v\u1eadt li\u1ec7u ph\u00f9 h\u1ee3p<\/li><li>ch\u1ea5t t\u1ea9y r\u1eeda ph\u00f9 h\u1ee3p<\/li><li>\u0111i\u1ec1u ki\u1ec7n v\u1ec7 sinh \u0111\u00fang<\/li><\/ul><div class=\"svt-kgrid svt-kgrid-2\"><div class=\"svt-kcard\"><i class=\"fa fa-sliders\" aria-hidden=\"true\"><\/i><h3>\u0110\u1eb7c \u0111i\u1ec3m ch\u00ednh c\u1ee7a v\u1ec7 sinh CIP<\/h3><ul class=\"svt-klist\"><li>V\u1eadn t\u1ed1c d\u00f2ng ch\u1ea3y trong \u0111\u01b0\u1eddng \u1ed1ng v\u00e0 van (t\u00f9y ti\u1ebft di\u1ec7n 1\u20134 m\/s)<\/li><li>Th\u1eddi gian s\u00fac r\u1eeda<\/li><li>\u00c1p su\u1ea5t phun t\u1ea1i c\u00e1c \u0111\u1ea7u phun r\u1eeda<\/li><li>Nhi\u1ec7t \u0111\u1ed9 c\u1ee7a dung d\u1ecbch v\u1ec7 sinh<\/li><li>Dung d\u1ecbch ki\u1ec1m s\u00fac r\u1eeda c\u00f3 ph\u1ee5 gia gi\u1eef c\u00e1c h\u1ea1t b\u1ea9n \u1edf tr\u1ea1ng th\u00e1i l\u01a1 l\u1eedng (h\u1ea1n ch\u1ebf t\u1ea1o b\u1ecdt)<\/li><li>S\u00fac r\u1eeda b\u1eb1ng axit \u0111\u1ec3 lo\u1ea1i b\u1ecf c\u1eb7n b\u00e1m nh\u01b0 c\u1eb7n v\u00f4i sau b\u01b0\u1edbc r\u1eeda ki\u1ec1m<\/li><li>Kh\u1eed tr\u00f9ng (SIP ho\u1eb7c h\u00f3a ch\u1ea5t)<\/li><li>Th\u1eddi gian t\u00e1c d\u1ee5ng v\u00e0 nhi\u1ec7t \u0111\u1ed9 c\u1ee7a ch\u1ea5t t\u1ea9y r\u1eeda<\/li><li>Quy m\u00f4 h\u1ec7 th\u1ed1ng<\/li><li>Quy tr\u00ecnh l\u1eb7p l\u1ea1i \u0111\u01b0\u1ee3c nh\u1edd v\u1eadn h\u00e0nh ho\u00e0n to\u00e0n t\u1ef1 \u0111\u1ed9ng<\/li><li>L\u1eadp h\u1ed3 s\u01a1 qu\u00e1 tr\u00ecnh v\u1ec7 sinh<\/li><\/ul><\/div><div class=\"svt-kcard\"><i class=\"fa fa-bullseye\" aria-hidden=\"true\"><\/i><h3>Nhi\u1ec7m v\u1ee5 c\u1ee7a v\u1ec7 sinh CIP\/SIP<\/h3><ul class=\"svt-klist\"><li>Lo\u1ea1i b\u1ecf ho\u00e0n to\u00e0n c\u1eb7n s\u1ea3n ph\u1ea9m<\/li><li>Lo\u1ea1i b\u1ecf m\u00e0ng sinh h\u1ecdc (biofilm)<\/li><li>Kh\u00f4ng c\u00f2n d\u01b0 l\u01b0\u1ee3ng ch\u1ea5t t\u1ea9y r\u1eeda<\/li><li>B\u1ed9 ph\u1eadn thi\u1ebft b\u1ecb v\u00e0 \u0111\u01b0\u1eddng \u1ed1ng v\u00f4 khu\u1ea9n<\/li><\/ul><\/div><\/div><h2>Tr\u00ecnh t\u1ef1 v\u1ec7 sinh CIP trong ng\u00e0nh d\u01b0\u1ee3c ph\u1ea9m<\/h2><ol class=\"svt-steps\"><li><span class=\"svt-step-n\">1<\/span><strong>Th\u1eed gi\u1eef \u00e1p<\/strong><span class=\"svt-step-tx\">Tr\u01b0\u1edbc ti\u00ean, ki\u1ec3m tra \u0111\u1ed9 k\u00edn c\u1ee7a h\u1ec7 th\u1ed1ng.<\/span><\/li><li><span class=\"svt-step-n\">2<\/span><strong>H\u00fat ch\u00e2n kh\u00f4ng v\u00e0 l\u00e0m ch\u1ea3y<\/strong><span class=\"svt-step-tx\">V\u1edbi s\u1ea3n ph\u1ea9m ch\u1ee9a ch\u1ea5t b\u00e9o, h\u1ec7 th\u1ed1ng \u0111\u01b0\u1ee3c h\u00fat ch\u00e2n kh\u00f4ng, c\u1eb7n s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c l\u00e0m ch\u1ea3y b\u1eb1ng h\u01a1i s\u1ea1ch v\u00e0 x\u1ea3 ra \u1edf d\u1ea1ng c\u00f4 \u0111\u1eb7c.<\/span><\/li><li><span class=\"svt-step-n\">3<\/span><strong>Tr\u00e1ng s\u01a1 b\u1ed9 b\u1eb1ng n\u01b0\u1edbc n\u00f3ng<\/strong><span class=\"svt-step-tx\">Tr\u00e1ng s\u01a1 b\u1ed9 b\u1eb1ng n\u01b0\u1edbc n\u00f3ng gi\u00fap lo\u1ea1i b\u1ecf ch\u1ea5t b\u1ea9n th\u00f4.<\/span><\/li><li><span class=\"svt-step-n\">4<\/span><strong>R\u1eeda ki\u1ec1m<\/strong><span class=\"svt-step-tx\">R\u1eeda b\u1eb1ng <a href=\"https:\/\/de.wikipedia.org\/wiki\/Lauge\" target=\"_blank\" rel=\"noopener\">ch\u1ea5t t\u1ea9y ki\u1ec1m<\/a>, n\u1ebfu c\u1ea7n k\u00e8m ph\u1ee5 gia gi\u00fap gi\u1eef c\u00e1c h\u1ea1t b\u1ea9n \u1edf tr\u1ea1ng th\u00e1i l\u01a1 l\u1eedng t\u1ed1t h\u01a1n.<\/span><\/li><li><span class=\"svt-step-n\">5<\/span><strong>Tr\u00e1ng l\u1ea1i b\u1eb1ng n\u01b0\u1edbc n\u00f3ng<\/strong><span class=\"svt-step-tx\">Khi x\u1ea3 c\u1ea1n, ch\u1ea5t t\u1ea9y r\u1eeda v\u00e0 c\u1eb7n s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c r\u1eeda tr\u00f4i ra ngo\u00e0i.<\/span><\/li><li><span class=\"svt-step-n\">6<\/span><strong>Tr\u00e1ng b\u1eb1ng Purified Water<\/strong><span class=\"svt-step-tx\">Ti\u1ebfp theo l\u00e0 tr\u00e1ng b\u1eb1ng n\u01b0\u1edbc tinh khi\u1ebft trong khi x\u1ea3 c\u1ea1n.<\/span><\/li><li><span class=\"svt-step-n\">7<\/span><strong>R\u1eeda axit<\/strong><span class=\"svt-step-tx\">Ch\u1ea5t t\u1ea9y axit lo\u1ea1i b\u1ecf c\u1eb7n v\u00f4i v\u00e0 c\u1eb7n ki\u1ec1m.<\/span><\/li><li><span class=\"svt-step-n\">8<\/span><strong>Tr\u00e1ng l\u1ea1i b\u1eb1ng Purified Water<\/strong><span class=\"svt-step-tx\">Sau \u0111\u00f3, h\u1ec7 th\u1ed1ng \u0111\u01b0\u1ee3c tr\u00e1ng th\u00eam m\u1ed9t l\u1ea7n n\u1eefa b\u1eb1ng n\u01b0\u1edbc tinh khi\u1ebft.<\/span><\/li><li><span class=\"svt-step-n\">9<\/span><strong>SIP \u2013 Sterilization in Place<\/strong><span class=\"svt-step-tx\">H\u00fat ch\u00e2n kh\u00f4ng khu v\u1ef1c thi\u1ebft b\u1ecb, \u0111i\u1ec1u ch\u1ec9nh \u00e1p su\u1ea5t h\u01a1i \u0111\u1ebfn v\u00f9ng qu\u00e1 \u00e1p v\u00e0 x\u1ea3 n\u01b0\u1edbc ng\u01b0ng.<\/span><\/li><li><span class=\"svt-step-n\">10<\/span><strong>S\u1ea5y kh\u00f4<\/strong><span class=\"svt-step-tx\">Cu\u1ed1i c\u00f9ng, h\u1ec7 th\u1ed1ng \u0111\u01b0\u1ee3c s\u1ea5y kh\u00f4 b\u1eb1ng ch\u00e2n kh\u00f4ng, v\u00ed d\u1ee5 v\u1edbi kh\u00ed c\u1ea5p v\u00f4 tr\u00f9ng n\u00f3ng.<\/span><\/li><\/ol><p class=\"svt-knote\">Tr\u00ecnh t\u1ef1 v\u00e0 th\u1eddi gian t\u1eebng b\u01b0\u1edbc c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh. N\u1ed3ng \u0111\u1ed9 dung d\u1ecbch v\u1ec7 sinh c\u0169ng c\u00f3 th\u1ec3 thay \u0111\u1ed5i. Ngo\u00e0i ra, c\u00e1c ch\u1ea5t t\u1ea9y r\u1eeda \u0111\u1eadm \u0111\u1eb7c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u1ed1i tr\u1ed9n trong m\u1ed9t m\u1ebb pha m\u1edbi th\u00e0nh dung d\u1ecbch v\u1ec7 sinh c\u00f3 hi\u1ec7u qu\u1ea3 t\u1ed1i \u01b0u (stack cleaning).<\/p><h2>Sterilization in Place (SIP)<\/h2><p>Sterilization in Place l\u00e0 ph\u01b0\u01a1ng ph\u00e1p ti\u1ec7t tr\u00f9ng t\u1ea1i ch\u1ed7 cho h\u1ec7 th\u1ed1ng thi\u1ebft b\u1ecb c\u00f4ng ngh\u1ec7 b\u1eb1ng h\u01a1i s\u1ea1ch. \u1ede \u0111\u00e2y c\u0169ng kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi. M\u1ecdi b\u1ed9 ph\u1eadn ti\u1ebfp x\u00fac v\u1edbi s\u1ea3n ph\u1ea9m \u0111\u1ec1u \u0111\u01b0\u1ee3c ti\u1ec7t tr\u00f9ng.<\/p><p>Quy tr\u00ecnh SIP th\u01b0\u1eddng s\u1eed d\u1ee5ng h\u01a1i s\u1ea1ch b\u00e3o h\u00f2a. \u0110\u1ec3 \u0111\u1ea1t nhi\u1ec7t \u0111\u1ed9 ti\u1ec7t tr\u00f9ng 121 \u00b0C, c\u1ea7n qu\u00e1 \u00e1p kho\u1ea3ng 1 bar. T\u00f9y y\u00eau c\u1ea7u, nhi\u1ec7t \u0111\u1ed9 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh v\u00e0 ghi nh\u1eadn theo \u00e1p su\u1ea5t h\u01a1i v\u00e0 th\u1eddi gian t\u00e1c d\u1ee5ng.<\/p><p>C\u00e1c b\u1ed9 ph\u1eadn c\u1ea7n ti\u1ec7t tr\u00f9ng n\u00ean \u0111\u01b0\u1ee3c h\u00fat ch\u00e2n kh\u00f4ng tr\u01b0\u1edbc khi ti\u1ec7t tr\u00f9ng b\u1eb1ng h\u01a1i. Nh\u1edd \u0111\u00f3 kh\u00f4ng h\u00ecnh th\u00e0nh t\u00fai kh\u00ed v\u00e0 nhi\u1ec7t \u0111\u1ed9 ph\u00e2n b\u1ed1 nhanh, \u0111\u1ed3ng \u0111\u1ec1u.<\/p><h2>H\u1ec7 th\u1ed1ng CIP t\u00edch h\u1ee3p trong h\u1ec7 th\u1ed1ng thi\u1ebft b\u1ecb c\u00f4ng ngh\u1ec7<\/h2><p>M\u1ecdi b\u1ec1 m\u1eb7t b\u00ean trong c\u1ee7a h\u1ec7 th\u1ed1ng c\u00f4ng ngh\u1ec7 \u0111\u01b0\u1ee3c v\u1ec7 sinh ch\u1ee7 y\u1ebfu b\u1eb1ng quy tr\u00ecnh Cleaning in Place. M\u00e1y \u0111\u1ed3ng h\u00f3a \u0111\u00f3ng vai tr\u00f2 b\u01a1m tu\u1ea7n ho\u00e0n dung d\u1ecbch CIP. C\u00e1c thi\u1ebft b\u1ecb kh\u00e1c bao g\u1ed3m v\u00ed d\u1ee5:<\/p><ul class=\"svt-checks\"><li>\u1ed0ng h\u00fat ch\u1ea5t l\u1ecfng<\/li><li>C\u1ea7n h\u00fat b\u1ed9t<\/li><li>B\u1ed3n pha<\/li><\/ul><p>H\u1ec7 th\u1ed1ng tr\u1ed9n n\u00ean \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf sao cho c\u00e0ng nhi\u1ec1u s\u1ea3n ph\u1ea9m \u0111i v\u00e0o b\u1ed3n \u0111\u00edch c\u00e0ng t\u1ed1t, k\u1ec3 c\u1ea3 \u0111\u01b0\u1eddng c\u1ea5p cho m\u00e1y chi\u1ebft r\u00f3t. Nh\u1edd v\u1eady, l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m c\u00f2n s\u00f3t l\u1ea1i \u00edt v\u00e0 ch\u1ec9 m\u1ed9t l\u01b0\u1ee3ng t\u1ed1i thi\u1ec3u \u0111i v\u00e0o n\u01b0\u1edbc th\u1ea3i.<\/p><p>V\u00ec v\u1eady, \u0111\u00e1y b\u1ed3n, c\u00e1nh g\u1ea1t th\u00e0nh v\u00e0 b\u1ec1 m\u1eb7t, c\u0169ng nh\u01b0 chi\u1ec1u d\u00e0i v\u00e0 \u0111\u1ed9 d\u1ed1c c\u1ee7a \u0111\u01b0\u1eddng x\u1ea3 sau m\u00e1y \u0111\u1ed3ng h\u00f3a c\u1ea7n \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf sao cho h\u1ea7u nh\u01b0 kh\u00f4ng c\u00f2n l\u01b0\u1ee3ng t\u1ed3n \u0111\u1ecdng. Ngo\u00e0i ra, m\u1ecdi \u0111\u01b0\u1eddng \u1ed1ng b\u00ean trong h\u1ec7 th\u1ed1ng c\u00f4ng ngh\u1ec7 \u0111\u1ec1u ph\u1ea3i n\u1eb1m trong quy tr\u00ecnh CIP.<\/p><p>C\u00e1c thi\u1ebft b\u1ecb b\u1ed5 sung cho quy tr\u00ecnh CIP kh\u00f4ng \u0111\u01b0\u1ee3c tr\u1edf th\u00e0nh ngu\u1ed3n nhi\u1ec5m b\u1ea9n v\u1eadt l\u00fd, h\u00f3a h\u1ecdc hay vi sinh. Ngo\u00e0i ra, c\u00e1c khe h\u1edf kh\u00f4ng kh\u00ed (air break) tr\u01b0\u1edbc m\u1ecdi \u0111i\u1ec3m n\u1ed1i n\u01b0\u1edbc th\u1ea3i ng\u0103n ng\u1eeba t\u00e1i nhi\u1ec5m khu\u1ea9n.<\/p><h2>Quy tr\u00ecnh v\u1ec7 sinh trong h\u1ec7 th\u1ed1ng m\u1ef9 ph\u1ea9m<\/h2><p>Quy tr\u00ecnh CIP trong h\u1ec7 th\u1ed1ng m\u1ef9 ph\u1ea9m th\u01b0\u1eddng g\u1ed3m c\u00e1c b\u01b0\u1edbc sau:<\/p><ol class=\"svt-steps\"><li><span class=\"svt-step-n\">1<\/span><strong>S\u00fac r\u1eeda n\u00f3ng m\u1ed9t chi\u1ec1u<\/strong><span class=\"svt-step-tx\">C\u00e1c b\u1ed9 ph\u1eadn thi\u1ebft b\u1ecb v\u00e0 \u0111\u01b0\u1eddng \u1ed1ng \u0111\u01b0\u1ee3c s\u00fac r\u1eeda b\u1eb1ng n\u01b0\u1edbc n\u00f3ng theo d\u00f2ng m\u1ed9t chi\u1ec1u. Nh\u1edd \u0111\u00f3, c\u1eb7n s\u1ea3n ph\u1ea9m \u0111i th\u1eb3ng v\u00e0o n\u01b0\u1edbc th\u1ea3i m\u00e0 kh\u00f4ng l\u00e0m b\u1ea9n thi\u1ebft b\u1ecb CIP.<\/span><\/li><li><span class=\"svt-step-n\">2<\/span><strong>R\u1eeda ki\u1ec1m<\/strong><span class=\"svt-step-tx\">Dung d\u1ecbch ki\u1ec1m kho\u1ea3ng 70 \u00b0C \u0111\u01b0\u1ee3c tu\u1ea7n ho\u00e0n v\u00e0 lo\u1ea1i b\u1ecf m\u1ecdi c\u1eb7n s\u1ea3n ph\u1ea9m nh\u00ecn th\u1ea5y \u0111\u01b0\u1ee3c. Sau \u0111\u00f3 tr\u00e1ng l\u1ea1i khi x\u1ea3 c\u1ea1n b\u1ed3n.<\/span><\/li><li><span class=\"svt-step-n\">3<\/span><strong>R\u1eeda axit v\u00e0 kh\u1eed tr\u00f9ng<\/strong><span class=\"svt-step-tx\">Ch\u1ea5t t\u1ea9y axit h\u00f2a tan c\u1eb7n v\u00f4i. Sau \u0111\u00f3 n\u01b0\u1edbc n\u00f3ng \u0111\u01b0\u1ee3c tu\u1ea7n ho\u00e0n cho \u0111\u1ebfn khi thi\u1ebft b\u1ecb \u0111\u1ea1t 80\u201390 \u00b0C trong m\u1ed9t kho\u1ea3ng th\u1eddi gian x\u00e1c \u0111\u1ecbnh (kh\u1eed tr\u00f9ng b\u1eb1ng nhi\u1ec7t).<\/span><\/li><li><span class=\"svt-step-n\">4<\/span><strong>Tr\u00e1ng l\u1ea1nh<\/strong><span class=\"svt-step-tx\">Cu\u1ed1i c\u00f9ng, s\u00fac r\u1eeda tu\u1ea7n ho\u00e0n b\u1eb1ng n\u01b0\u1edbc kh\u1eed kho\u00e1ng l\u1ea1nh qua c\u00e1c \u0111\u1ea7u phun r\u1eeda v\u00e0 tr\u00e1ng l\u1ea1i khi x\u1ea3 c\u1ea1n.<\/span><\/li><\/ol><p>C\u00e1c b\u01b0\u1edbc n\u00e0y c\u00f3 th\u1ec3 n\u1ed1i ti\u1ebfp nhau, l\u1eb7p l\u1ea1i ho\u1eb7c l\u01b0\u1ee3c b\u1ecf \u2013 c\u00f3 ho\u1eb7c kh\u00f4ng d\u00f9ng th\u00eam ch\u1ea5t t\u1ea9y r\u1eeda.<\/p><p class=\"svt-knote\">T\u00f9y ch\u1ecdn, c\u1ea3m bi\u1ebfn \u0111\u1ed9 d\u1eabn \u0111i\u1ec7n gi\u00e1m s\u00e1t ch\u1ea5t l\u01b0\u1ee3ng v\u1ec7 sinh (n\u01b0\u1edbc tr\u00e1ng cu\u1ed1i &lt; 50 \u00b5S\/cm \u1edf 20 \u00b0C).<\/p><p>C\u00f4ng ty <strong>SEEFRIED Verfahrenstechnik GmbH<\/strong> h\u1ed7 tr\u1ee3 Qu\u00fd kh\u00e1ch thi\u1ebft k\u1ebf h\u1ec7 th\u1ed1ng CIP v\u00e0 SIP, x\u00e2y d\u1ef1ng tr\u00ecnh t\u1ef1 CIP v\u00e0 mua s\u1eafm thi\u1ebft b\u1ecb c\u00f4ng ngh\u1ec7 li\u00ean quan.<\/p><h2>C\u00e2u h\u1ecfi th\u01b0\u1eddng g\u1eb7p v\u1ec1 h\u1ec7 th\u1ed1ng CIP v\u00e0 SIP<\/h2><h3>CIP v\u00e0 SIP kh\u00e1c nhau nh\u01b0 th\u1ebf n\u00e0o?<\/h3><p>CIP (Cleaning in Place) v\u1ec7 sinh b\u1ed3n ch\u1ee9a, \u0111\u01b0\u1eddng \u1ed1ng v\u00e0 van m\u00e0 kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi. SIP (Sterilization in Place) sau \u0111\u00f3 ti\u1ec7t tr\u00f9ng c\u00e1c b\u1ed9 ph\u1eadn ti\u1ebfp x\u00fac v\u1edbi s\u1ea3n ph\u1ea9m \u2013 c\u0169ng kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi \u2013 b\u1eb1ng h\u01a1i s\u1ea1ch, th\u01b0\u1eddng \u1edf 121 \u00b0C.<\/p><h3>Nh\u1eefng y\u1ebfu t\u1ed1 n\u00e0o quy\u1ebft \u0111\u1ecbnh hi\u1ec7u qu\u1ea3 v\u1ec7 sinh?<\/h3><p>Y\u1ebfu t\u1ed1 quy\u1ebft \u0111\u1ecbnh l\u00e0 v\u1eadn t\u1ed1c d\u00f2ng ch\u1ea3y (trong \u0111\u01b0\u1eddng \u1ed1ng kho\u1ea3ng 1\u20134 m\/s), nhi\u1ec7t \u0111\u1ed9, n\u1ed3ng \u0111\u1ed9 v\u00e0 th\u1eddi gian t\u00e1c d\u1ee5ng c\u1ee7a dung d\u1ecbch v\u1ec7 sinh, \u00e1p su\u1ea5t phun t\u1ea1i \u0111\u1ea7u phun r\u1eeda, ch\u1ea5t t\u1ea9y r\u1eeda ph\u00f9 h\u1ee3p v\u00e0 k\u1ebft c\u1ea5u h\u1ee3p v\u1ec7 sinh kh\u00f4ng c\u00f3 v\u00f9ng d\u00f2ng ch\u1ea3y y\u1ebfu.<\/p><h3>M\u1ed9t quy tr\u00ecnh v\u1ec7 sinh CIP \u0111i\u1ec3n h\u00ecnh di\u1ec5n ra nh\u01b0 th\u1ebf n\u00e0o?<\/h3><p>Th\u00f4ng th\u01b0\u1eddng g\u1ed3m tr\u00e1ng s\u01a1 b\u1ed9 b\u1eb1ng n\u01b0\u1edbc n\u00f3ng, r\u1eeda b\u1eb1ng ch\u1ea5t t\u1ea9y ki\u1ec1m, tr\u00e1ng trung gian, r\u1eeda b\u1eb1ng ch\u1ea5t t\u1ea9y axit \u0111\u1ec3 lo\u1ea1i c\u1eb7n v\u00f4i v\u00e0 tr\u00e1ng cu\u1ed1i b\u1eb1ng n\u01b0\u1edbc tinh khi\u1ebft \u2013 t\u00f9y y\u00eau c\u1ea7u, ti\u1ebfp theo l\u00e0 SIP v\u00e0 s\u1ea5y kh\u00f4. Tr\u00ecnh t\u1ef1 v\u00e0 th\u1eddi gian c\u00e1c b\u01b0\u1edbc c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh.<\/p><h3>Hi\u1ec7u qu\u1ea3 v\u1ec7 sinh \u0111\u01b0\u1ee3c ki\u1ec3m tra nh\u01b0 th\u1ebf n\u00e0o?<\/h3><p>V\u00ed d\u1ee5 b\u1eb1ng c\u1ea3m bi\u1ebfn \u0111\u1ed9 d\u1eabn \u0111i\u1ec7n trong n\u01b0\u1edbc tr\u00e1ng cu\u1ed1i (gi\u00e1 tr\u1ecb tham chi\u1ebfu &lt; 50 \u00b5S\/cm \u1edf 20 \u00b0C). Quy tr\u00ecnh ho\u00e0n to\u00e0n t\u1ef1 \u0111\u1ed9ng v\u00e0 c\u00f3 h\u1ed3 s\u01a1 \u0111\u1ea3m b\u1ea3o k\u1ebft qu\u1ea3 l\u1eb7p l\u1ea1i \u0111\u01b0\u1ee3c.<\/p><h2 class=\"svt-pcta-h\">H\u00e3y li\u00ean h\u1ec7 v\u1edbi ch\u00fang t\u00f4i<\/h2><div class=\"svt-pcta svt-pcta-m\"><div class=\"svt-pcta-tx\">Ch\u00fang t\u00f4i s\u1eb5n l\u00f2ng t\u01b0 v\u1ea5n cho Qu\u00fd kh\u00e1ch v\u1ec1 h\u1ec7 th\u1ed1ng CIP v\u00e0 SIP \u2013 qua \u0111i\u1ec7n tho\u1ea1i theo s\u1ed1 <a href=\"tel:+494203789492\">+49 4203 789492<\/a> ho\u1eb7c qua email <a href=\"mailto:i&#110;f&#111;&#64;s&#45;&#118;t.&#110;&#101;t\">info&#64;s-&#118;&#116;.&#110;&#101;t<\/a>.<\/div><div class=\"svt-pcta-btns\"><a class=\"svt-btn svt-btn-primary\" href=\"https:\/\/www.s-vt.net\/vi\/contact\/?produkt=Verfahrenstechnische%20Beratung\">Y\u00eau c\u1ea7u t\u01b0 v\u1ea5n<\/a><a class=\"svt-btn svt-btn-ghost\" href=\"https:\/\/www.s-vt.net\/vi\/process-engineering\/\">T\u1ea5t c\u1ea3 d\u1ecbch v\u1ee5 t\u01b0 v\u1ea5n<\/a><\/div><\/div><h2>C\u00e1c d\u1ecbch v\u1ee5 t\u01b0 v\u1ea5n kh\u00e1c<\/h2><div class=\"svt-sgrid\"><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/homogenizing-technology\/\"><span>C\u00f4ng ngh\u1ec7 \u0111\u1ed3ng h\u00f3a<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/mixing-homogenizing-processes\/\"><span>C\u00f4ng ngh\u1ec7 qu\u00e1 tr\u00ecnh trong khu\u1ea5y v\u00e0 \u0111\u1ed3ng h\u00f3a<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/temperature-control-systems\/\"><span>H\u1ec7 th\u1ed1ng \u0111i\u1ec1u nhi\u1ec7t<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/transfer-systems\/\"><span>H\u1ec7 th\u1ed1ng chuy\u1ec3n li\u1ec7u<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/plant-engineering-project-execution\/#steuerungen\"><span>H\u1ec7 th\u1ed1ng \u0111i\u1ec1u khi\u1ec3n<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/software-interface-description\/\"><span>Ph\u1ea7n m\u1ec1m v\u00e0 m\u00f4 t\u1ea3 giao di\u1ec7n<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/di-water-plants\/\"><span>H\u1ec7 th\u1ed1ng n\u01b0\u1edbc kh\u1eed kho\u00e1ng &amp; \u0111\u01b0\u1eddng \u1ed1ng v\u00f2ng<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/steam-plants\/\"><span>H\u1ec7 th\u1ed1ng h\u01a1i n\u01b0\u1edbc<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/plant-engineering-project-execution\/#lagertanks\"><span>B\u1ed3n l\u01b0u tr\u1eef &amp; th\u00f9ng ch\u1ee9a<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><a class=\"svt-scard\" href=\"https:\/\/www.s-vt.net\/vi\/pipelines\/\"><span>\u0110\u01b0\u1eddng \u1ed1ng<\/span><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/a><\/div><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Service\",\"name\":\"Thi\u1ebft k\u1ebf h\u1ec7 th\u1ed1ng CIP v\u00e0 SIP\",\"description\":\"T\u01b0 v\u1ea5n thi\u1ebft k\u1ebf, tr\u00ecnh t\u1ef1 v\u1ec7 sinh v\u00e0 mua s\u1eafm h\u1ec7 th\u1ed1ng CIP v\u00e0 SIP c\u0169ng nh\u01b0 thi\u1ebft k\u1ebf h\u1ec7 th\u1ed1ng h\u1ee3p v\u1ec7 sinh cho s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m v\u00e0 m\u1ef9 ph\u1ea9m.\",\"url\":\"https:\/\/www.s-vt.net\/vi\/cip-sip-systems\/\",\"provider\":{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.s-vt.net\/#seefried\",\"name\":\"SEEFRIED Verfahrenstechnik GmbH\",\"url\":\"https:\/\/www.s-vt.net\/\",\"telephone\":\"+49 4203 789492\"},\"areaServed\":\"Worldwide\"},{\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"CIP v\u00e0 SIP kh\u00e1c nhau nh\u01b0 th\u1ebf n\u00e0o?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"CIP (Cleaning in Place) v\u1ec7 sinh b\u1ed3n ch\u1ee9a, \u0111\u01b0\u1eddng \u1ed1ng v\u00e0 van m\u00e0 kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi. SIP (Sterilization in Place) sau \u0111\u00f3 ti\u1ec7t tr\u00f9ng c\u00e1c b\u1ed9 ph\u1eadn ti\u1ebfp x\u00fac v\u1edbi s\u1ea3n ph\u1ea9m \u2013 c\u0169ng kh\u00f4ng c\u1ea7n th\u00e1o r\u1eddi \u2013 b\u1eb1ng h\u01a1i s\u1ea1ch, th\u01b0\u1eddng \u1edf 121 \u00b0C.\"}},{\"@type\":\"Question\",\"name\":\"Nh\u1eefng y\u1ebfu t\u1ed1 n\u00e0o quy\u1ebft \u0111\u1ecbnh hi\u1ec7u qu\u1ea3 v\u1ec7 sinh?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Y\u1ebfu t\u1ed1 quy\u1ebft \u0111\u1ecbnh l\u00e0 v\u1eadn t\u1ed1c d\u00f2ng ch\u1ea3y (trong \u0111\u01b0\u1eddng \u1ed1ng kho\u1ea3ng 1\u20134 m\/s), nhi\u1ec7t \u0111\u1ed9, n\u1ed3ng \u0111\u1ed9 v\u00e0 th\u1eddi gian t\u00e1c d\u1ee5ng c\u1ee7a dung d\u1ecbch v\u1ec7 sinh, \u00e1p su\u1ea5t phun t\u1ea1i \u0111\u1ea7u phun r\u1eeda, ch\u1ea5t t\u1ea9y r\u1eeda ph\u00f9 h\u1ee3p v\u00e0 k\u1ebft c\u1ea5u h\u1ee3p v\u1ec7 sinh kh\u00f4ng c\u00f3 v\u00f9ng d\u00f2ng ch\u1ea3y y\u1ebfu.\"}},{\"@type\":\"Question\",\"name\":\"M\u1ed9t quy tr\u00ecnh v\u1ec7 sinh CIP \u0111i\u1ec3n h\u00ecnh di\u1ec5n ra nh\u01b0 th\u1ebf n\u00e0o?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Th\u00f4ng th\u01b0\u1eddng g\u1ed3m tr\u00e1ng s\u01a1 b\u1ed9 b\u1eb1ng n\u01b0\u1edbc n\u00f3ng, r\u1eeda b\u1eb1ng ch\u1ea5t t\u1ea9y ki\u1ec1m, tr\u00e1ng trung gian, r\u1eeda b\u1eb1ng ch\u1ea5t t\u1ea9y axit \u0111\u1ec3 lo\u1ea1i c\u1eb7n v\u00f4i v\u00e0 tr\u00e1ng cu\u1ed1i b\u1eb1ng n\u01b0\u1edbc tinh khi\u1ebft \u2013 t\u00f9y y\u00eau c\u1ea7u, ti\u1ebfp theo l\u00e0 SIP v\u00e0 s\u1ea5y kh\u00f4. Tr\u00ecnh t\u1ef1 v\u00e0 th\u1eddi gian c\u00e1c b\u01b0\u1edbc c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh.\"}},{\"@type\":\"Question\",\"name\":\"Hi\u1ec7u qu\u1ea3 v\u1ec7 sinh \u0111\u01b0\u1ee3c ki\u1ec3m tra nh\u01b0 th\u1ebf n\u00e0o?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"V\u00ed d\u1ee5 b\u1eb1ng c\u1ea3m bi\u1ebfn \u0111\u1ed9 d\u1eabn \u0111i\u1ec7n trong n\u01b0\u1edbc tr\u00e1ng cu\u1ed1i (gi\u00e1 tr\u1ecb tham chi\u1ebfu < 50 \u00b5S\/cm \u1edf 20 \u00b0C). Quy tr\u00ecnh ho\u00e0n to\u00e0n t\u1ef1 \u0111\u1ed9ng v\u00e0 c\u00f3 h\u1ed3 s\u01a1 \u0111\u1ea3m b\u1ea3o k\u1ebft qu\u1ea3 l\u1eb7p l\u1ea1i \u0111\u01b0\u1ee3c.\"}}]}]}<\/script><\/div><\/div><\/div><\/div><\/div><\/div><\/section><\/section><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","footnotes":""},"class_list":["post-18988","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>H\u1ec7 th\u1ed1ng CIP\/SIP cho d\u01b0\u1ee3c ph\u1ea9m &amp; m\u1ef9 ph\u1ea9m | SEEFRIED<\/title>\n<meta name=\"description\" content=\"Gi\u1ea3i th\u00edch CIP v\u00e0 SIP: tr\u00ecnh t\u1ef1 v\u1ec7 sinh, c\u00e1c y\u1ebfu t\u1ed1 \u1ea3nh 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