Used Symex CML125

For sale is a high-quality Symex CML125 vacuum mixing and homogenizing system, designed for applications in the pharmaceutical, cosmetics, and food industries.

The Symex CML125 is a complete process system for mixing, dispersing, homogenizing, heating, cooling, and evacuating, and is ideally suited for production and pilot applications. Depending on the industry, this type of system is also referred to as a homogenizing mixer, vacuum mixer, emulsifying plant or ointment and cream manufacturing plant.

Designed for the production of creams, gels, ointments, and pastes.

Symex CML125 – Condition & Availability

✔ Industrial-grade system in pharmaceutical design
✔ Pressure- and vacuum-resistant vessel
✔ Designed according to PED / AD2000 (TÜV certified)
✔ Documentation including operating manuals and test certificates

📍 Location: Weyhe near Bremen

Status: available (as of October 2026)

Why buy a Symex CML125?

The Symex CML125 is a proven system for demanding processes:

✔ Fully-fledged vacuum homogenizing mixer
✔ Suitable for emulsions, suspensions, and high-viscosity products
✔ Precise process control for reproducible results
✔ Direct suction of powders and liquids
✔ Hygienic and CIP-compatible design
✔ Ideal for production and scale-up

Typical applications of the Symex CML125

• Cosmetic creams and lotions
• Pharmaceutical products (ointments, gels)
• Suspensions and emulsions
• Pilot and production batches

The system is specifically designed for mixing processes such as liquid/liquid and solid/liquid, as well as heating, cooling, evacuation, and cleaning.

Technical Highlights of the Symex CML125

• Vacuum and pressure-resistant mixing vessel
• Comb paddle agitator with scrapers and baffles
• Homogenizer (rotor/stator) in the vessel base
• Large and small circulation for flexible process control
• Direct suction of powders and liquids into the homogenizer
• CIP system with rotating cleaning nozzles (Toftejorg)
• Electrical control with Siemens S7 and touch panel
• Vacuum system with liquid ring pump
• Temperature control unit for heating and cooling

Vessel

• Usable volume: approx. 125 liters
• Minimum volume: approx. 25–40 liters
• Total volume: approx. 218 liters
• Product chamber pressure range: -1 / +2 bar
• Temperature: up to approx. 133 °C
• Heating/cooling jacket: up to +4 bar / 151 °C
• Design: cylindrical with dished end
• Insulated container with stainless steel cladding
• Pharmaceutical-grade design

Materials and surfaces

• Product-contacting surfaces: 316L stainless steel
• Seals: Viton (FDA compliant)
• Surface roughness: Ra < 0.4 µm
• Welded, hygienically finished surfaces

Agitator

• Comb paddle agitator with PTFE scrapers
• Two baffles for optimal mixing
• Speed: approx. 19–82 rpm
• Power: approx. 6.5 kW
• Reversible operation with timer
• Water-cooled Motor
• Designed for high-viscosity products up to approx. 100,000 mPas

Homogenizer

• Type: SYMEX HFDA 250 (Rotor/Stator)
• Power: approx. 22 kW
• Speed: up to approx. 5,013 rpm
• Shear rate: approx. 5 – 21 m/s
• Flow rate: approx. 250 L/min
• Double mechanical seal (SiC/SiC)
• Barrier fluid system with cooling and monitoring
• Sterile design without dead space

Recirculation systems

• Large circulation DN50 for homogenization and CIP
• Small circulation DN50 for small quantities
• Tangential return for optimal venting

Suction system

• Liquid suction (DN25) with interval control
• Powder suction (DN25) with dosing control
• Direct suction into the homogenizer
• Optimized for dust-free and low-loss operation Raw material addition

CIP system

• At least 3 rotating cleaning nozzles (Toftejorg)
• Additional washing balls in the lid and handhole
• CIP connection via recirculation system
• Hygienic cleaning of all product-contacting areas

Temperature and vacuum system

• Temperature control unit with heat exchanger (steam/cooling water)
• Secondary circuit with pump system
• Liquid ring vacuum pump
• Suction capacity: approx. 130 m³/h
• Minimum pressure: approx. 33 mbar

Automation & control

• Siemens S7-300 PLC control
• Panel PC for operation
• Control of agitator, homogenizer, vacuum, and temperature
• Batch control and process visualization
• Trend recording (pressure, temperature, speed)

Standards & documentation

• Machinery Directive 98/37/EC
• Pressure Equipment Directive 97/23/EC
• PED / AD2000
• Documentation incl. Operating instructions, circuit diagrams and test

documentation

• Optional IQ/OQ qualification
• Complete pharmaceutical-compliant documentation

• Ex-Works delivery
• Turnkey project available (including commissioning)
• 12-month warranty (excluding wear parts)
• International shipping available

Request a Symex CML125 quote

Contact us now for a free, no-obligation quote:

📞 +49 4203 789492

📧 info@s-vt.net
Please provide your complete company details.

Frequently Asked Questions about the Symex CML125

Can the Symex CML125 be inspected?

Yes. The unit is located in Weyhe near Bremen, Germany, and can be inspected by appointment.

What batch sizes are possible with the Symex CML125?

The working volume is approx. 125 liters, the minimum volume approx. 25 to 40 liters. The total vessel volume is approx. 218 liters.

Which products is the unit suitable for?

Creams, lotions, gels, ointments, pastes, emulsions and suspensions. The agitator is designed for highly viscous products up to approx. 100,000 mPas.

Is the Symex CML125 suitable for GMP applications?

Yes. Product-contact surfaces are made of stainless steel 316L with a surface roughness of Ra < 0.4 µm, the seals are FDA-compliant, the unit is CIP capable and designed according to PED / AD2000. IQ/OQ qualification is optionally available.

Do you ship internationally?

Yes, international shipping is possible. Delivery is Ex-Works or, on request, as a turn-key project including commissioning.

Is there a warranty?

Yes, we provide a 12-month warranty (excluding wear parts).

This is a non-binding offer from SEEFRIED Verfahrenstechnik GmbH as an independent supplier.
There is no business relationship with the manufacturer.

All trademarks mentioned are the property of their respective owners and are used solely for the purpose of identifying the products offered.

This is not an offer from the manufacturer.