Symex CML1000

High-performance Symex CML1000 vacuum mixing and homogenizing system, designed for the industrial production of emulsions, suspensions, and liquid products.

This complete production system is ideal for demanding processes in the pharmaceutical, cosmetics, and food industries and combines:

✔ Mixing
✔ Homogenizing
✔ Dispersing
✔ Heating & Cooling
✔ Vacuum Processing

Symex CML1000 – Condition & Availability

✔ This machine (Symex CML1000) has already been sold. Currently available: Symex CML125, Symex P1000 and more used homogenizer mixers.

✔ Large-scale industrial system
✔ Pressure and vacuum resistant vessel
✔ TÜV certified (PED / AD2000)
✔ Documentation including IQ/OQ-relevant documents

📍 Location: Weyhe near Bremen

Why buy a Symex CML1000?

The CML1000 belongs to the high-end class of industrial homogenizing mixers:

✔ Batch size up to 1000 liters
✔ Co-twister homogenizer (rotor/rotor system)
✔ High shear rate + flexible process control
✔ Ideal for scale-up and series production
✔ GMP-compliant design

Complete process chain integrated into a single system

Typical applications:

• Pharmaceutical liquids
• Cosmetic emulsions and creams
• Gels and suspensions
• Food products

The system supports, among other things:

• Liquid/liquid mixtures
• Solid/liquid mixtures
• Vacuum processes
• Pressure emptying
• CIP cleaning

Vessel & Construction

• Usable volume: approx. 1000 liters
• Minimum volume: approx. 250 liters
• Total volume: approx. 1370 liters
• Pressure range in product chamber: up to approx. 4 bar abs.
• Temperature: up to approx. 132 °C
• Heating/cooling jacket: up to approx. 158 °C
• Double-walled vessel with 2-zone heating
• Fully insulated (stainless steel jacket)
• Pressure draining & sterilization possible

Agitator system (coaxial agitator)

• Central agitator + peripheral agitator
• Power: approx. 7.8 kW each
• Speed ​​ranges:
  • Central: 7 – 120 rpm
  • Peripheral: 2 – 38 rpm
• Inclined blade agitator + frame agitator
• PTFE scraper for optimal heat transfer
• Reversible operation (automatically controlled)
• Optimized for highly viscous media up to approx. 100,000 mPas

Homogenizer – SYMEX Co-Twister (HFDC 500)

A real highlight of the system:

• Rotor/rotor system (not a classic rotor/stator!)
• Power: up to approx. 2 × 26 kW
• Speed: up to approx. 4800 rpm
• Shearing speed: up to approx. 62 m/s

Advantages:

✔ Independent control of speed & shearing action
✔ Variable process modes (e.g., shearing vs. throughput)
✔ Ideal for sensitive emulsions

Technological advantage over standard homogenizers

Recirculation system & product guidance

• Short circulation (for small batches)
• Recirculation line for intensive homogenization
• Tangential return for venting

✔ Prevents dead zones
✔ Consistent product quality

Suction system (powders & liquids)

• Direct suction into the homogenizer
• Separate suction for powders and liquids
• PLC-controlled dosing

✔ Low-dust raw material feed
✔ Immediate dispersion in the shear gap

Suction directly in front of the homogenizer

CIP cleaning system

• Rotating Spray nozzles (Toftejorg)
• 360° cleaning
• Integrated CIP line

✔ Fully cleanable
✔ Pharmaceutical/GMP compliant

Integrated automatic cleaning

Temperature and vacuum system

• Heating/cooling circuit with heat exchangers
• Temperature control via Pt100 sensor
• Liquid ring vacuum pump
• Vacuum: up to approx. 33 mbar
• Suction capacity: approx. 190 m³/h

✔ Precise process conditions

Electrical systems and controls

• Siemens S7-300 PLC
• Touch panel operation
• Fully automatic process control

✔ Control of:

• Agitator
• Homogenizer
• Temperature
• Vacuum
• Suction processes

Central process visualization

Standards and documentation

• Machinery Directive 98/37/EC
• Pressure Equipment Directive 97/23/EC
• PED / AD2000

Documentation includes:

✔ Operating instructions
✔ Maintenance schedules
✔ Circuit diagrams
✔ Calibration documentation
✔ Material certificates (3.1B)

Pharmaceutical-compliant documentation available

Delivery & Handling

• Ex-Works delivery
• Turnkey projects available (including commissioning)
• 12-month warranty (excluding wear parts)
• International shipping available

Looking for a similar machine?

We can help you source a comparable machine – contact us now for a free, no-obligation enquiry:

📧 info@s-vt.net
Please provide your complete company details.

Currently available alternatives to the Symex CML1000

The Symex CML1000 has been sold. The following used machines are available at short notice and can be inspected in Weyhe near Bremen, Germany:

• Becomix RW2500 + AB1200 – homogenizing mixer for large batches with pre-mix vessel
• Becomix RW320 – homogenizing mixer, approx. 100–320 L, GMP, CIP/SIP
• Symex P1000 – pharma storage tank / agitated vessel 1,000 L (2 units)

See all offers in our overview of used homogenizing mixers & process equipment.

Frequently Asked Questions about the Symex CML1000

Is the Symex CML1000 still available?

No, this machine has already been sold. The technical data on this page is provided for reference, e.g. when looking for a comparable machine.

What were the key specifications of the Symex CML1000?

Working volume approx. 1,000 L (min. approx. 250 L), total volume approx. 1,370 L, up to approx. 4 bar abs. and approx. 132 °C, coaxial agitator (central and peripheral agitator approx. 7.8 kW each) with PTFE scrapers, 2-zone heating, for highly viscous products up to approx. 100,000 mPas.

What alternatives to the Symex CML1000 are available?

Currently available are, among others, Becomix RW2500 + AB1200, Becomix RW320, Symex P1000. We are happy to advise which machine suits your product, batch size and GMP requirements.

Can you source a comparable used machine?

Yes. With our procurement support we search specifically for a suitable used vacuum homogenizing mixer. Tell us your product, required volume, viscosity and requirements such as GMP, CIP/SIP or explosion protection – by phone at +49 4203 789492 or by email to info@s-vt.net.

This is a non-binding offer from SEEFRIED Verfahrenstechnik GmbH as an independent supplier.
There is no business relationship with the manufacturer.

All trademarks mentioned are the property of their respective owners and are used solely for the purpose of identifying the products offered.

This is not an offer from the manufacturer.