High quality homogenizing mixers, their performance and flexibility can significantly reduce production times and costs. The special efficiency of such agitators is due to a variety of factors: It should, therefore, be ensured that the rotor-stator-system is protected against extraneous parts. The infinitely variable speed adjustment and the design of the agitator, as well as that of the homogenizer, should allow highly efficient agitation and homogenization. Also on this point, care should be taken that the design is GMP-compliant. Intensive homogenization in the vessel as well as in the circulation procedure and homogenization of small quantities should be possible in the agitator. A particularly high value should be placed on clean scraping in the rotation direction change operation. The efficient suction of powder and the dispersion into liquids and semi-solids should be possible without great dust emission in the vessel. According to requirements, a pressure and vacuum-tight design should be considered, in order to ensure consistent qualities. The SIP and aseptic GMP design, as well as the integrated CIP design should be suitable for compliance with all hygiene regulations.