for SALE

Symex CML1000

for SALE

Buy a used Symex CML1000 – Vacuum homogenizing mixer for industrial production | Pharmaceutical version

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Symex CML1000 vacuum mixing and homogenizing system for sale (1000 liters)

For sale is a high-performance Symex CML1000 vacuum mixing and homogenizing system, designed for the industrial production of emulsions, suspensions, and liquid products.

This complete production system is ideal for demanding processes in the pharmaceutical, cosmetics, and food industries and combines:

✔ Mixing
✔ Homogenizing
✔ Dispersing
✔ Heating & Cooling
✔ Vacuum Processing

Symex CML1000 – Condition & Availability

✔ Large-scale industrial system
✔ Pressure and vacuum resistant vessel
✔ TÜV certified (PED / AD2000)
✔ Documentation including IQ/OQ-relevant documents

📍 Location: Weyhe near Bremen

Why buy a Symex CML1000?

The CML1000 belongs to the high-end class of industrial homogenizing mixers:

✔ Batch size up to 1000 liters
✔ Co-twister homogenizer (rotor/rotor system)
✔ High shear rate + flexible process control
✔ Ideal for scale-up and series production
✔ GMP-compliant design

Complete process chain integrated into a single system

Typical applications:

  • Pharmaceutical liquids
  • Cosmetic emulsions and creams
  • Gels and suspensions
  • Food products


The system supports, among other things:

  • Liquid/liquid mixtures
  • Solid/liquid mixtures
  • Vacuum processes
  • Pressure emptying
  • CIP cleaning

Technical Data – Symex CML1000

Vessel & Construction

  • Usable volume: approx. 1000 liters
  • Minimum volume: approx. 250 liters
  • Total volume: approx. 1370 liters
  • Pressure range in product chamber: up to approx. 4 bar abs.
  • Temperature: up to approx. 132 °C
  • Heating/cooling jacket: up to approx. 158 °C
  • Double-walled vessel with 2-zone heating
  • Fully insulated (stainless steel jacket)
  • Pressure draining & sterilization possible


Agitator system (coaxial agitator)

  • Central agitator + peripheral agitator
  • Power: approx. 7.8 kW each
  • Speed ​​ranges:
    • Central: 7 – 120 rpm
    • Peripheral: 2 – 38 rpm
  • Inclined blade agitator + frame agitator
  • PTFE scraper for optimal heat transfer
  • Reversible operation (automatically controlled)
  • Optimized for highly viscous media up to approx. 100,000 mPas

Homogenizer – SYMEX Co-Twister (HFDC 500)

A real highlight of the system:

  • Rotor/rotor system (not a classic rotor/stator!)
  • Power: up to approx. 2 × 26 kW
  • Speed: up to approx. 4800 rpm
  • Shearing speed: up to approx. 62 m/s


Advantages:

✔ Independent control of speed & shearing action
✔ Variable process modes (e.g., shearing vs. throughput)
✔ Ideal for sensitive emulsions

Technological advantage over standard homogenizers

Recirculation system & product guidance

  • Short circulation (for small batches)
  • Recirculation line for intensive homogenization
  • Tangential return for venting

✔ Prevents dead zones
✔ Consistent product quality

Suction system (powders & liquids)

  • Direct suction into the homogenizer
  • Separate suction for powders and liquids
  • PLC-controlled dosing

✔ Low-dust raw material feed
✔ Immediate dispersion in the shear gap

Suction directly in front of the homogenizer

CIP cleaning system

  • Rotating Spray nozzles (Toftejorg)
  • 360° cleaning
  • Integrated CIP line

✔ Fully cleanable
✔ Pharmaceutical/GMP compliant

Integrated automatic cleaning

Temperature and vacuum system

  • Heating/cooling circuit with heat exchangers
  • Temperature control via Pt100 sensor
  • Liquid ring vacuum pump
  • Vacuum: up to approx. 33 mbar
  • Suction capacity: approx. 190 m³/h

✔ Precise process conditions

Electrical systems and controls

  • Siemens S7-300 PLC
  • Touch panel operation
  • Fully automatic process control

✔ Control of:

  • Agitator
  • Homogenizer
  • Temperature
  • Vacuum
  • Suction processes

Central process visualization

Standards and documentation

  • Machinery Directive 98/37/EC
  • Pressure Equipment Directive 97/23/EC
  • PED / AD2000

Documentation includes:

✔ Operating instructions
✔ Maintenance schedules
✔ Circuit diagrams
✔ Calibration documentation
✔ Material certificates (3.1B)

Pharmaceutical-compliant documentation available


Delivery and processing

Delivery & Handling

  • Ex-Works delivery
  • Turnkey projects available (including commissioning)
  • 12-month warranty (excluding wear parts)
  • International shipping available


Request a Symex CML1000 quote

Contact us now for a free, no-obligation quote:

📧 info@s-vt.net
Please provide your complete company details.

Disclaimer

This is a non-binding offer from SEEFRIED Verfahrenstechnik GmbH as an independent supplier.
There is no business relationship with the manufacturer.

All trademarks mentioned are the property of their respective owners and are used solely for the purpose of identifying the products offered.

This is not an offer from the manufacturer.

Do you have questions?

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